CHF 10' This module gives the basic concepts of general toxicology: pharmaco- and toxicokinetics absorption, distribution, metabolism, excretion, bioavailability, absorption rate constant, half-life, volume of distribution, clearance, area under the curvetoxicodynamics or mechanistic toxicology non receptor and receptor mediated mechanisms, binding, dose- response relationship, potency versus efficacy, agonism, antagonism, synergy, potentiating, tolerance, sensitizationbasic principles of toxicology administration or exposure routes, role of metabolites, accumulation, characteristics of toxic effects, toxicity targets.
Descriptive toxicology presents an overview of the effects of the main toxic agents which will be further developed in different modules. This module in e-learning format and face-to-face lectures, is divided into two parts that can be followed independently.
Part A must be passed multiple choice questions in order to attend any other module. The evaluation of Part B is based on students' written assignments and oral presentations article or case.
The final mark is a combination of marks A and B. Module 1A costs CHF. Module 1B costs CHF. This module describes the metabolic pathways involved in the biotransformation of xenobiotics leading to poisonous compounds, detoxification or producing toxic intermediates, as well as their circadian control.
The students will learn to interpret methods to quantify or predict cytochrome P activities. Toxicokinetic and toxicodynamic principles and physiologically based toxicokinetic modelling will be presented. The student will be able to understand, describe and interpret the impact of gene polymorphisms on the safety of medications, drugs and environmental agents toxicogeneticsas well as the technologies involved in their assessment. Finally, the role of toxicology in drug development will be described.
This transversal module is the largest module of the programme. Its content is linked to several other modules as it describes the basic physiology of liver, kidney, heart, lungs, brain and skin this background knowledge will be delivered partly as e-learningas well as their specific susceptibilities to toxicants.
General mechanisms of toxicity, such as oxidative stress, inflammation, induction of apoptosis and necrosis, as well as mechanisms of toxicity specific to the different organs will be taught by internationally recognized researchers based on their expertise in these fields. The most important analytical techniques spectral or separation approaches used for determining potential toxic substances in different matrices are presented, including hyphenation with mass spectrometry.
Students will be able to choose and evaluate appropriate analytical tools related to toxicological situations. The evaluation of this module is divided into two parts. The first part consists of individual responses of thought questions related to scientific articles after the face-to face session.
Questions are given on the e-learning platform homework. The second part is an oral individual exam 15 minutes preparation and 15 minutes discussion based on a critical analysis of a scientific article dealing with an analytical technique. This course introduces the fundamentals of epidemiology and the principles of the statistical methods most frequently encountered in human toxicology. While it includes short formal presentations of concepts and techniques, emphasis is placed on their application to real data in toxicology.
Seminars are held in a computer room, where hands-on sessions focus on conducting analyses and interpreting results. They should also be able to carry out simple data analyses using statistical software.
Completion of homework assignments proposed during the course is a prerequisite for participation in the exam.Andrologie et de biologie de la reproduction Laboratoire d'. Angiologie Service d'. Antalgie Centre d'. Autisme Centre cantonal. Biobanque institutionnelle de Lausanne. Bioinformatique Institut suisse de. Biologie computationnelle at UNIL. Biologie de la conservation Laboratoire de. Biologie vasculaire et des tumeurs Laboratoire de. Biostatistics Service.
Cancer and immunology PhD Programme in. Cancer Research Ludwig. Cardiologie Service de. Cardiovascular and metabolism PhD Program.
Chimie clinique Service de. Chirurgie cardiaque Service de. Chirurgie plastique et de la main Service de. Chirurgie septique Centre de. Chirurgie thoracique Service de. Chirurgie vasculaire Service de. CHUV - Centre hospitalier universitaire vaudois.The world is experiencing an unprecedented impact due to the COVID pandemic, which has also led to a mental health crisis for millions of people around the globe, in particular young people.
Are you a working professional who seeks to acquire and deepen personal skills in international health together with management and administration? Join the session online! Watch Temitope Adebayo's award-winning flash talk about air pollution being a public health problem in South Africa. As a PhD student at Swiss TPH, she aims to provide scientific evidence to strengthen air quality policy in South Africa, and ensure that air pollution becomes a priority research area. In order to reach the goal of eliminating dog-mediated human rabies byintegrated strategies, political will and innovations are needed.
Swiss TPH researchers edited a special edition on the elimination of dog rabies in West and Central Africa, which includes the latest results from research and practice. New content covers Corona viruses in animals and humans, linking global health security with emerging infectious disease threats. How can we eradicate malaria? Explore cutting-edge science and technology, and examine policies needed, to control and eliminate malaria. As part of our efforts to continue to advance malaria knowledge, the free, open-access online MalariaX course has been extended to 30 April Insecticide-treated bed nets are the most widely adopted preventive measure against malaria, and represent an effective form of prevention for at-risk populations.
A project by HIV continues to be a major global health issue, having claimed almost 33 million lives. Despite lots of progress made in the past decade, more thanchildren die from Malaria each year. Most of these deaths could be avoided through timely diagnosis and Taking Science to Impact. Mental Health for All The world is experiencing an unprecedented impact due to the COVID pandemic, which has also led to a mental health crisis for millions of people around the globe, in particular young people.
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Preview this item Preview this item. Publisher: Lyon : Ed. Subjects Hospital utilization. Medical statistics.
View all subjects More like this Similar Items. Allow this favorite library to be seen by others Keep this favorite library private. Find a copy in the library Finding libraries that hold this itemEven when you think it is a quite day of football, you can bet our tipster has found a hidden gem bet for you. Every day of the year, we cover four different bets in our free football tips page. Below I will explain each one in detail.
These betting tips below are the best ways to bet with our tips we feel and is how we track our long term profit. It doesn't mean this is the only way for you to bet though you can use our bets however you want long term.
We try and keep it simple and over the years the forms of bets we use may change to extract the most profit from our betting tips. Our super single is one football bet we pick everyday which our tipsters feel is nailed on and certain to win.
The odds on this vary from 1. We keep track of all our bets throughout the year, and our track record from our football super singles is very positive.
Our football accumulator is also a big earner across our tips pages, with a lot of big winners coming throughout the year. The accumulator varies massively in size throughout the season, with popular days having up to 12 selections and the quieter days having sometimes as little of 4-5.
If you like to build you own accas regularly, you have got to check out our stats page, it has everything you need. Each day we will also bring you our best both teams to score predictions. Our hit rate on both teams to score (BTTS) is way in the positive profit, taking all of our information from our in depth stats. Our lucky 15 is one of the biggest pay outs if it wins.
If we are being honest, this is a bet that lands every once in awhile, but when you do win, get ready to celebrate because you will have a lot of money to show for it.
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In short, it is a bet that involves four selections, and will be placed 15 times to make sure you have a return at the end. All of our football tips and predictions are released around 8pm (20:00) each day for the following day, this includes our BTTS acca, win accumulator and super single football bet.
This gives you loads of time to get your bets on and also get the best prices before they come in. This gives our expert tipsters the whole day before to research and find the very best bets for the following day to try and make us all money in the short and long term.
At SBAT there is no limit to the amount we cover on a daily, monthly and yearly basis. A lot of tips you will find on the internet will be those from the big leagues such as the Premier League, Championship, La Liga, Serie A, Bundesliga, Ligue 1, etc. Yes we provide bets for you 365 days of the year, this means Saturday and Sunday accas. We understand that Saturday betting is normally a punters dream especially with the amount of football games on.
This means on Saturday it is often easy to build a nice Saturday acca or even on Sundays you can get a good accumulator together.
Our weekend football betting tips are up around the same time as any others, we try and get them up around 20:00 the night before. This gives you plenty of time to get your winning bets on. We will update these bets daily, and all bets will be on the site by 12:00 each day. Time League Match 14:15 Premier League Liverpool v Everton 16:30 Premier League Manchester Utd v Manchester City 17:30 La Liga Levante v Bilbao 19:45 La Liga Villarreal v Barcelona Best Odds: 6.
Time League Match 12:00 Premier League Southampton v Arsenal 14:00 Serie A Napoli v Fiorentina 19:45 La Liga Villarreal v Barcelona 20:00 Ligue 1 Marseille v St Etienne Best Odds: 8.My music can be heard at YouTube. This definitely has opened my eyes or should i say ears.
Some very good pointers as well as confirmations of what i am doing right and wrong. I will definitely keep this close. Thank you so much!!. Get a Lenovo Z50. Have a friend assemble one according to the latest recommended specs. It does matter if you use Mac or PC??. Hope that clears it up.
I read all your tips. I needed this, thanks. Feel free to check me out on SoundCloud as well. I am very satisfied with my sounds but I am struggling to connect them together (transition between sounds and beats).
I love this article. I have had a hard time finding good resources online, and already figured out most of this stuff the hard way, like adjusting parameters for 5 minutes, or not getting good samples, and especially getting depressed at the pros work. Thank you ZacThis is a fantastic list but I think you have a few hefty and untrue statements in there. Free software will not make generally make great music. I use an ancient Cubase and its workflow smashes Reaper.
Also you have made out in your list that EQ and compression are of little importance in terms of general use and mixing and mastering. Volume mixing and automating makes a surprisingly good difference but EQ makes the difference between it sounding like someone is holding a cushion over your speaker, or not. Compression can hold a track together and give a lot of power and punch. Also with the good headphones, not necessary. I would add to the list that work flow is important. Like it all I tell myself a lot of this and never listen, but sinks in when you hear it elsewhere!!.
Thanks for putting this together. Search for: Articles Mixing Recording Producing Mastering Videos Latest Essentials Compression EQ Drums Hip-Hop Low End Vocals Guitar Effects Pro Audio Files Tutorials Partners Free Sample Pack Become a Member Search for: Articles Mixing Recording Producing Mastering Videos Latest Essentials Compression EQ Drums Hip-Hop Low End Vocals Guitar Effects SPONSORED OFFER googletag. There was an error submitting your subscription. Free Video on Mixing Low End Download a FREE 40-minute tutorial from Matthew Weiss on mixing low end.
We just sent a download link to your inbox. COM Matt Mann Bangin track. Rolling Tartana Beatz Thanks man. Luis Castaneda I read all your tips.
Thank you Zac Phuzion1 This is a fantastic list but I think you have a few hefty and untrue statements in there. Other than the above superb list. Ankit Kumar Great article. Matt This is some good shot right here. I should print it off and put it on the wall above my mac vido Great advice. Mathew Fok Disagree with a few points, but agree with a lot for the most part.